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Image Search Results
Journal: Journal of Neuroscience
Article Title: Long-Latency Reductions in Gamma Power Predict Hemodynamic Changes That Underlie the Negative BOLD Signal
doi: 10.1523/jneurosci.2339-14.2015
Figure Lengend Snippet: Figure5. Spatial–temporalrepresentationofhemodynamicchangesevokedbysingle-impulsestimulation,sortedbygammapower(30–80Hz)fromtheuppercorticallayers(channels3–8) ofthesurroundelectrode(300–2000msafterstimuluspresentation).A,Hemodynamicresponseinsurroundregion,evokedbysingle-impulsestimulationofthewhiskerpad,averageofalltrials. B,Hemodynamicresponseinsurroundregion,averageoftrials(33%)havingtheleastgammapowerinthesurroundregion,intheuppercorticallayers(channels3–8).C,Hemodynamic response in surround region, average of trials (33%) having the most gamma power in the surround region, in the upper cortical layers. D, In vivo grayscale image of thinned cranial window from a single representative subject, with regions of interest around the two recording electrodes used for time-series generation. E–G, Averaged Hbt changes, evoked by single-impulse stimulation from a single representative subject, all trials (100%), least gamma (33%) and most gamma (33%) respectively, and gamma power recorded from surround electrode. Hbt changes in the whisker region response (black) and surround region response (green). Montage of images shows spatial maps of micromolar changes in Hbt. Each is averaged over a second and represents a corresponding time point in the stimulation trial. Increases in Hbt are toward the red color range, with blue representing negative changes. H, In vivo grayscale camera image of thinned cranial window from a single representative subject, with a series of concentric rings centered on the whisker barrel electrode. These were used toselectpixelsforselectionofdataasafunctionofdistanceawayfromtheelectrode.I–K,Hbtchanges,withdatafromalltrials,leastgammapower(33%)andmostgammapower(33%) respectively. The y-axis represents distance away from the tip of the whisker electrode, with each row in the image generated from pixels within each concentric ring. Stimulation represented with arrows. Error bars represent SEM across subjects. Responses averaged across subjects (n 10), except for single subject (D–H).
Article Snippet: After piercing the dura with a 27 gauge needle, a stereotaxic arm (Kopf Instruments) was used to insert the 16-
Techniques: In Vivo, Whisker Assay, Generated